Recently I ran into a problem helping a client with their Office 365 Hybrid Configuration. We couldn’t get the Office 365 Hybrid Configuration Wizard (HCW) to launch. We tried running it in Internet Explorer and Google Chrome without success.
It seems the Office 365 team changed the HCW from a standalone Windows executable to a Click-To-Run (C2R) executable. The biggest benefit of using C2R is that whenever it is clicked, the latest version of the program is downloaded and launched.
The problem was something broke the Default Programs association for “.application” extensions. If you open the Default Programs control panel and look at the “.application” filetype, this is what you’ll see:
Change the “.application” file type to be opened with Internet Explorer. Go back to the HCW link and click it.